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4.2 Doseresponse characteristics of HDL-C in different diseases HDL-C is one of the blood lipid components that most characteristically exhibits a U-shaped doseresponse curve, and its functional quality may be more important than its absolute quantity in the assessment of metabolic disease risk

Although the trial-based evidence for metformin monotherapy from UKPDS is not as strong as with the novel drugs tested in recent CVOTs, it is supported by extensive observations from everyday clinical practice70 , 113 , 114 , 115

Stability studies indicated ORI@CPD-Lipo stored at 4 C for 21 days exhibited no significant changes in appearance or physicochemical properties, and the solution remained homogeneous and stable

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